![]() ![]() ![]() ![]() The presence of a paraprotein or abnormal free light chain ratio not meeting criteria for smoldering myeloma or active myeloma (i.e.A pre-malignant disorder with a 5% annual risk of progression to myeloma.Not meeting the above criteria for active myelomaĭefinition of Monoclonal Gammopathy of Undetermined Significance (MGUS).Clonal bone marrow plasma cells 10-60%, or serum paraprotein (IgG or IgA) ≥30g/L, or urinary paraprotein >500mg/24hrs, AND:.Ratio of involved : uninvolved serum free light chains >100.>60% clonal plasma cells in bone marrow.Anaemia (not attributable to another cause).Renal failure (not attributable to another cause).Hypercalcaemia (not attributable to hyperparathyroidism or other malignancy).Clonal plasma cells constitute >10% of nucleated cells in a bone marrow biopsy OR biopsy-proven plasmacytoma, AND additionally at least one of:.Myeloma is a cancer of plasma cells, commonly associated with a monoclonal paraprotein and bone damage.Presentation, diagnosis and treatment of myeloma and MGUS – for doctors, medical students and exams Myeloma and monoclonal gammopathy of undetermined significance (MGUS) ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |